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Some researchers have identified the main efflux transport proteins of SL was multidrug resistance-associated protein (MRP2) and breast cancer resistance protein (BCRP), and compounds that inhibited the efflux transport proteins MRP2 and BCRP could enhance the absorption and activity of SL (Xie et al., 2019), such as piperine or tangeretin (Yuan et al., 2018)
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It occurs more commonly in females than males and is precipitated by hormones and UV exposure from sunlight and light sources
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