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In a 2025 rat alkali-burn model, topical BPC-157 (10 µg/mL) closed wounds 43 % faster by day 7 compared with saline controls.(pmc.ncbi.nlm.nih.gov) A 2024 pharmacokinetic study found an oral half-life under 30 minutes and intramuscular bioavailability between 14 % and 51 % in two species.(pmc.ncbi.nlm.nih.gov) Common compounded strengths range from 500 µg capsules to 2 mg/mL injectables and 1 µg/g creams, but none are FDA-approved.(fda.gov) The FDA Pharmacy Compounding Advisory Committee reviewed BPC-157 bulk substances on July 23 2026 and advised against adding them to the 503A list, citing insufficient safety and efficacy data.(fda.gov) No controlled human study has evaluated BPC-157 for wrinkles, acne scars, or post-surgical keloids as of September 2026.(compoundedevidence.com) Bottom line: Lab and animal findings are promising, but BPC-157 still lacks the human trials and regulatory green light needed to recommend it for skin rejuvenation