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Collectively, these findings demonstrate that PTSD arises through a complex interplay of gut dysbiosis, neuroendocrine disruption, immune activation, and altered neurotransmission, firmly implicating the microbiota–MGBA in the pathophysiology of trauma-related disorders

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These signals are primarily delivered by DCs and macrophages, which not only capture and present antigens but also express co-stimulatory molecules and MHC molecules to deliver the second signal to T cells

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