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Brain Insulin Resistance Targets Refractory Depression Outcomes - Los Angeles Times
For example, in colorectal cancer (CRC), tumor-derived lanosterol can be taken up by CD8⁺ T cells, where it suppresses the mevalonate pathway and reduces prenylation and activity of KRAS proto-oncogene, GTPase (KRAS), ultimately promoting T cell apoptosis and impairing their antitumor function
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15 Arterial thrombosis causes reduced blood flow (ischemia), resulting in reduced oxygen and nutrient delivery and ischemic tissue damage
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