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Acute and long-term administration of palmitoylcarnitine induces muscle-specific insulin resistance in mice

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Größe:500 Gramm (1.1 lbs)

Specifically, increased expression of peroxisome proliferator-activated receptor-γ coactivator-1α protein, a key regulator of mitochondrial biosynthesis, disrupts the mitochondrial structure and leads to dysfunctional proliferation, which is involved in the development of certain cardiac diseases, such as heart failure and atherosclerosis (45)